Participants required for national study testing ivermectin and other drugs against COVID-19


A study is underway to test the effectiveness of existing drugs against the coronavirus. UT Health San Antonio says only 14 participants have signed up.

SAN ANTONIO – A study is underway to test the effectiveness of existing drugs against the coronavirus. UT Health San Antonio says only 14 participants have signed up. Researchers need 15,000 people.

The ACTIV-6 study is being conducted nationwide, and UT Health San Antonio is part of the large-scale effort to find new treatments for coronaviruses. The study is testing three drugs approved by the FDA that are used to treat other health problems. Researchers want to know if these drugs can be reused to fight symptoms of the coronavirus.

The first drug tested is fluticasone, a commonly prescribed inhaled steroid for asthma. The second drug is fluvoxamine, which is typically used to treat depression and obsessive-compulsive disorder. The third drug in the study is ivermectin, which is used to treat parasitic infections in humans and to deworm pets and livestock.

“The 3 drugs in the study have at least been shown to be effective in one way or another in smaller trials or at least have theoretical advantages,” said Dr. Thomas F. Patterson, professor of medicine and chief. , Division of Infectious Diseases at UT Health San Antonio. “Ivermectin is probably one of the most controversial of the three studied. A lot of press around ivermectin. Some people have sworn it’s the last biggest. In careful clinical trials, these have yet to be conducted in a broad enough way to say that it is safe and effective.

Local lead researcher Dr Patterson said the goal was to find treatment options earlier and help people avoid hospital altogether. He pointed out the Regeneron antibody treatment which can be given by injection.

“The problem is, it’s extremely expensive and the supply is very limited, so it’s obviously very difficult for patients who need it to get this kind of therapy,” he explained. .

KENS 5 spoke with one of the study participants, Laura Najvar, Laboratory Manager at UT Health San Antonio. A researcher for over 30 years, she understands that data is a powerful tool. Najvar said she was infected with the coronavirus several weeks ago. She had a cough, high fever, chills, and lost her taste and smell. She was chosen to take fluticasone to treat her symptoms for the study.

“For me it was kind of an obvious situation because I understand the importance,” Najvar said. “Get the data collected to hopefully help establish the best potential therapies, safe therapies, and more effective therapies for COVID-19. “

Those interested in the study must be 30 years of age or older, have tested positive for COVID-19 in the past 10 days, and have had at least two symptoms of COVID-19 for 7 days or less.

There is no charge for participants. If you are selected to take any of the drugs, the drugs will be shipped to your home free of charge. In addition, there are no in-person visits to the clinics. Participants will be invited to complete online surveys and speak with a member of the study team throughout the process.

You can call 833-385-1880 or register online.

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